2D Materials for Next Generation Healthcare Technologies

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Welcome

2D-Health capitalises on the world-leading expertise and research infrastructure on graphene and 2D materials available at the University of Manchester (UoM) to develop future therapies and generate innovative healthcare technology platforms by ascertaining UK leadership in biotech and pharmaceutical development.

grafpheneThe 2D-Health team aims to utilise unique properties offered by G2D materials and technologies to develop innovative solutions for specific unmet clinical needs in wound care and management (relevant to diabetes and orthopaedics); tissue rehabilitation by electrical stimulation (relevant to dementia); cell therapeutics (relevant to cardiovascular disease); and immunotherapeutics (relevant to cancer).

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Research Themes

Theme I: Smart Membranes in Trauma and Wound Care

In this theme, the aim is to develop G2D-based membranes for topical applications to accelerate  wound healing and to promote wound antimicrobial resistance. ‘Smart’ membranes are envisioned by: a) control of selective permeability via chemical or physical modification for specific ions, water and other small molecules to modulate biological responses;…

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Theme II: 2D Inks for Imaging Cell Therapies

In this theme, the aim is to design G2D inks to label and non-invasively track cell populations administered in cell therapy protocols. The G2D inks will be fabricated to offer multiple signals (Raman, photoluminescence, NIR, magnetic, radiological) relevant to biomedical imaging, by: a) selecting and synthesising molecules used as the…

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Theme III: 2D Sheets for Cancer Immunotherapy

In this theme, the focus of 2D-Health is cancer immunotherapy, i.e., the mobilisation of the body’s own immune defences against a malignancy. The most common approach in this field is the programming of CD8+ cytotoxic T lymphocytes (CTLs) against tumour cells. In this perspective, a unique feature offered by graphene…

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